About this Medication
- How does this medication work? What will it do for me?
- How should I use this medication?
- What form(s) does this medication come in?
- Who should NOT take this medication?
- What side effects are possible with this medication?
- Are there any other precautions or warnings for this medication?
- What other drugs could interact with this medication?
How does this medication work? What will it do for me?
Indacaterol belongs to the class of medications called long-acting beta agonist bronchodilators. It is used to treat chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema. It works by relaxing the muscles in the walls of the small air passages in the lungs. This helps open up the airways, making breathing easier, preventing symptoms such as wheezing and shortness of breath. Indacaterol can start to work within 5 minutes of inhalation, and its effects can last up to 24 hours.
Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are using this medication, speak to your doctor. Do not stop using this medication without consulting your doctor.
Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.
How should I use this medication?
Indacaterol - mometasone is inhaled into the lungs through the mouth using the Breezhaler™ inhaler device. Do not swallow the capsules.
The starting dose of indacaterol - mometasone is based on your current dose of mometasone and the severity of your asthma symptoms. Your doctor will determine the correct dose for you.
The contents of one capsule are to be inhaled once daily, using the Breezhaler™ inhaler device that comes in the package with the medication. Your health care professional should show you how to use the device. If you are not sure about how to use the device, contact your doctor or pharmacist for advice.
Indacaterol - mometasone is intended as a preventative medication only. Do not use it to relieve difficulty breathing. If you need fast relief from asthma symptoms, use your fast-acting "reliever" (or "rescue") medication such as formoterol, terbutaline, or salbutamol.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are using the medication without consulting your doctor.
When used regularly, this medication helps to prevent episodes of severe difficulty breathing. Regular daily use is important for its effectiveness, even when you are not experiencing any symptoms. After inhaling the dose, rinse your mouth with water and spit it out.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
It is important to take this medication exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store this medication at room temperature. Protect it from light and moisture by keeping the capsules in the blister until you are ready to use a dose. Keep this and all medications out of the reach of children. Discard the old inhaler device and use the new one that comes with each package of medication.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
What form(s) does this medication come in?
Each hard gelatin capsule containing powder for inhalation, contains 173 µg of indacaterol acetate equivalent to 150 µg of indacaterol and 80 µg of mometasone furoate. The delivered dose of 150/80 µg (the dose that leaves the mouthpiece of the inhaler) is equivalent to 125 µg indacaterol, and 62.5 µg mometasone furoate. Nonmedicinal ingredients: gelatin and lactose (as monohydrate).
Each hard gelatin capsule containing powder for inhalation, contains 173 µg of indacaterol acetate equivalent to 150 µg of indacaterol and 160 µg of mometasone furoate. The delivered dose of 150/160 µg (the dose that leaves the mouthpiece of the inhaler) is equivalent to 125 µg indacaterol, and 127.5 µg mometasone furoate. Nonmedicinal ingredients: gelatin and lactose (as monohydrate).
Each hard gelatin capsule containing powder for inhalation, contains 173 µg of indacaterol acetate equivalent to 150 µg of indacaterol and 320 µg of mometasone furoate. The delivered dose of 150/320 µg (the dose that leaves the mouthpiece of the inhaler) is equivalent to 125 µg indacaterol, and 260 µg mometasone furoate. Nonmedicinal ingredients: gelatin and lactose (as monohydrate).
Who should NOT take this medication?
Do not use indacaterol if you:
- are allergic to indacaterol or any ingredients of the medication
- have asthma
- are experiencing sudden, severe symptoms of COPD
What side effects are possible with this medication?
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.
The side effects listed below are not experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor.
The following side effects have been reported by at least 1% of people taking this medication. Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
- irritation or pain of the mouth or throat
- muscle cramps
- upper respiratory tract infection (e.g., runny nose, sore throat)
Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
- COPD symptoms (breathlessness, wheezing, cough) do not improve or if they worsen during treatment
- rapid or pounding heartbeat
Stop taking the medication and seek immediate medical attention if any of the following occur:
- bronchospasm with wheezing or coughing and difficulty breathing
- breathing problems that worsen quickly
- symptoms of low potassium levels (e.g., muscle weakness, muscle spasms, or an abnormal heart rhythm)
- symptoms of an allergic reaction (e.g., fainting from low blood pressure, rash or itching or swelling of the face and throat)
Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking this medication.
Are there any other precautions or warnings for this medication?
Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.
Asthma: The safety and efficacy of this medication have not been established for people with asthma. Indacaterol belongs to the class of medication called long-acting beta-agonists (LABA). LABAs have been shown in a study to increase the risk of asthma-related deaths. Indacaterol should not be used to treat asthma.
Bronchospasm: Occasionally, inhaled medications may cause the airways to spasm and close up (bronchospasm), which makes breathing even more difficult and can be life-threatening. If you experience increased difficulty breathing after using a dose of indacaterol, seek immediate medical attention.
Diabetes: Indacaterol may cause a loss of blood glucose control and glucose tolerance may change. People with diabetes may find it necessary to monitor their blood sugar more frequently while using this medication.
If you have diabetes or are at risk for developing diabetes, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Heart problems: This medication can cause increased heart rate and blood pressure, as well as rapid or irregular heart beat or abnormal electrical signal called "prolonged QT interval". These effects may worsen symptoms of heart disease. If you have heart disease such as angina, congestive heart failure, or arrhythmia, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed. Contact your doctor as soon as possible if you develop symptoms of heart problems such as shortness of breath, chest pain, rapid heartbeat, or swollen ankles.
Low potassium levels: Indacaterol may cause decreased levels of potassium in the blood. This can cause abnormal heart rhythms, weakness, fatigue, muscle cramps or constipation. If you experience any of these symptoms, contact your doctor.
Lactose allergy: This medication contains lactose (milk sugar) and a small amount of milk proteins. It is possible that people who have a severe milk protein allergy may have an allergic reaction to this medication. Speak to your doctor if you have any concerns.
Seizures: If you have a history of epilepsy or medical conditions that increase the risk of seizures, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Sudden symptoms of COPD: Indacaterol is not a "reliever" or "rescue" medication. If you start developing acute symptoms such as breathlessness, wheezing, and cough, you should use your "reliever" medication for rapid relief of your symptoms. It is very important that you have your "reliever" medication with you at all times. Seek emergency medical help if your breathing problems worsen quickly or if you use your rescue medication but it does not relieve your breathing problems.
Thyroid gland problems: If you have thyroid disease, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Pregnancy: This medication should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking this medication, contact your doctor immediately.
Breast-feeding: It is not known if indacaterol passes into breast milk. If you are breast-feeding and are taking this medication, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: The safety and effectiveness of using this medication have not been established for people age 18 and under.
What other drugs could interact with this medication?
There may be an interaction between indacaterol and any of the following:
- amphetamines (e.g., dextroamphetamine, lisdexamfetamine)
- antipsychotics (e.g., chlorpromazine, clozapine, haloperidol, loxapine, olanzapine, quetiapine, risperidone)
- "azole" antifungals (e.g., itraconazole, ketoconazole, voriconazole)
- beta-blockers (e.g., metoprolol, propranolol, timolol)
- beta 2 agonists (e.g., salbutamol, formoterol, terbutaline)
- decongestant cold medications (e.g., phenylephrine, pseudoephedrine)
- decongestant eye drops and nose sprays (e.g., naphazoline, oxymetazoline, xylometazoline)
- loop diuretics (water pills; bumetanide, furosemide)
- monoamine oxidase inhibitors (MAOIs; e.g., moclobemide, phenelzine, rasagiline, selegiline, tranylcypromine)
- theophyllines (e.g., aminophylline, oxtriphylline, theophylline)
- thiazide diuretics (water pills; e.g., hydrochlorothiazide, indapamide, metolazone)
- tricyclic antidepressants (e.g., amitriptyline, clomipramine, desipramine, trimipramine) trimethoprim
- tyrosine kinase inhibitors (e.g., dasatinib, imatinib, nilotinib)
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
- stop taking one of the medications,
- change one of the medications to another,
- change how you are taking one or both of the medications, or
- leave everything as is.
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with this medication. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
All material copyright MediResource Inc. 1996 – 2022. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Source: www.medbroadcast.com/drug/getdrug/Atectura-Breezhaler